Research: Who We Are
Manish N. Shah, MD, MPH is a professor in the BerbeeWalsh Department of Emergency Medicine at the University of Wisconsin School of Medicine and Public Health, where he also serves as Vice Chair of Research and holds the John & Tashia Morgridge Chair of Emergency Medicine Research. Dr. Shah also serves as Co-Lead of the Care Research Core at the University of Wisconsin Alzheimer's Disease Research Center (ADRC).
Dr. Shah has developed an independently-funded research program dedicated to improving acute illness care for older adults, with a specific focus on developing and testing innovative models of care for acutely ill older adults. His goal is to prevent older adults from needing emergency department care or to develop substitutes for emergency department care. His recent work has been focused on improving the care of patients with dementia, especially using advanced technology and community health resources. His work has been funded through NIH early-career and mid-career development awards, including R01/U01 level grants from NIH, AHRQ, CDC, and the ADRC.
Dr. Shah has a deep commitment to training researchers and is increasingly dedicating his efforts to developing the next generation of independent scientists. He has personally mentored many undergraduate, graduate, and medical students; residents; fellows; and faculty. Many are now independent, grant-funded researchers who have had a profound influence within their own fields. His recently awarded NIH Mid-Career Investigator Award (K24) is allowing him to build the pipeline of geriatric emergency medicine researchers. At an institutional level, Dr. Shah is the Director of the NIH-funded KL2 Program at the University of Wisconsin’s Institute for Clinical and Translational Research, serving to train junior faculty researchers from various disciplines.
Dr. Patterson graduated from Pennsylvania State University with a bachelor of science in bioengineering and went on to complete a master’s degree in public health and a medical degree at the Northwestern University Feinberg School of Medicine. He continued at Northwestern for his residency training in emergency medicine, where he served as chief resident.
Dr. Patterson’s research interests are in clinical informatics and geriatric emergency medicine. His work aims to use routinely collected clinical data to generate actionable insights to improve the quality and safety of emergency care for older adults. To achieve these goals, Dr. Patterson works in collaboration with investigators from the business and engineering schools as well as in the department of biostatistics and medical informatics. His current work focuses on automated risk scoring to identify older adults at high risk for falling after ED visits, and automating referral to interventions to prevent future falls.
Dr. Patterson has also taken on the inaugural role as the physician informatics director of predictive analytics for the BerbeeWalsh Emergency Department at UW Health. In this role, Dr. Patterson works with department leadership to best use information technology to support clinical, educational, and research priorities. He advises on a range of issues, including optimizing the design, implementation, dissemination, evaluation and routine use of clinical data and information systems to improve healthcare quality, operational efficiency, educational programs, and research. Among other roles, he functions as a liaison between clinicians and health IT staff within the department and hospital, and provides input into implementation of new IT-related workflows in the department.
Dr. Michael Pulia is a tenure track, Assistant Professor and Director of the Emergency Care for Infectious Diseases (EC-ID) Research Program at the University of Wisconsin-Madison. He is also Director of Emergency Medicine Antimicrobial Stewardship. In these capacities, he leads a health services research program focused primarily on improving antimicrobial stewardship in the emergency department and acute care settings. Dr. Pulia’s program has been supported by intra- and extramural sources, including the Wisconsin Partnership Program and Agency for Healthcare Research and Quality (AHRQ).
Dr. Pulia has been an invited expert speaker at national and international conferences including IDWeek, the Society for Academic Emergency Medicine. and the International Symposium on Intensive Care and Emergency Medicine. In 2015, he was awarded the Barry M. Farr Humanitarian Award from the MRSA Survivors Network in recognition of his efforts to raise public awareness of bacterial resistance related to the overuse of antibiotics. He served a five-year term as Chair of the American Academy of Emergency Medicine’s (AAEM) Antimicrobial Stewardship Task Force. In this capacity, Dr. Pulia represented AAEM at the 2015 White House One Health Forum on Antimicrobial Stewardship and 2018 CDC Global Antimicrobial Resistance Challenge Kickoff event during the UN General Assembly. This task force was successful in raising awareness among thousands of emergency care providers about antimicrobial resistance and best practices in stewardship, culminating in the development of an antibiotic stewardship pledge for emergency care providers.
In the fall of 2020, Dr. Pulia was also invited to serve as the Co-Chair of the Wisconsin Department of Health Services Emergency Medicine/Urgent Care Antimicrobial Stewardship Subcommittee.
Dr. Repplinger graduated from the inaugural class of the University of Wisconsin Emergency Medicine Residency Program, where he served as Chief Resident. Prior to residency, Dr. Repplinger graduated from Georgetown University, earning an honors degree in Biochemistry, then finished his Medical Doctorate at the UW School of Medicine and Public Health. He also completed the Doctoral Program in Clinical Investigation offered by UW's Institute for Clinical and Translational Research. For three years, Dr. Repplinger was a UW KL2 Scholar (intramural career development award), but transitioned to an extramural K08 award through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) in 2016.
Dr. Repplinger’s research focuses on developing, validating, and disseminating radiation-free imaging technologies, particularly magnetic resonance (MR) imaging in order to reduce patients' exposure to ionizing radiation in the emergency department setting. His collaborative efforts have led to the routine clinical use of MR-pulmonary angiography to detect pulmonary embolism at UW. Dr. Repplinger's research team has also completed a prospective efficacy trial of contrast-enhanced MR to diagnose appendicitis in the general population, which was published in Radiology in 2018. Other current endeavors include evaluating the effectiveness of MR to diagnose pulmonary embolism and appendicitis in the community hospital setting and assessing barriers to the implementation of novel imaging algorithms for pulmonary embolism and appendicitis.
Using Team Science and Dissemination/Implementation Research skills learned from his emergency radiology core research program, Dr. Repplinger has more recently joined other research groups at UW Health to improve the care of patients with opioid use disorder in the Madison area. Current projects aim to increase co-prescribing of naloxone with opioids from the emergency department as well as increasing the use of buprenorphine for opioid withdrawal symptoms and long-term addiction treatment.
Dr. Ward completed both his undergraduate degree and medical school training here at UW. He was one of the first students to be awarded the Darren Bean Emergency Medicine Scholarship. He then moved on to Chicago to complete his residency at the University of Chicago. Upon graduation, he stayed on as faculty at the University of Chicago and returned to Madison in 2017.
Dr. Ward's main research focus is management of septic patients within the emergency department. He published a recent article in Critical Care Medicine showing that early fluid resuscitation improves survival for patients with severe sepsis or septic shock indiscriminate of potentially fluid volume sensitive conditions like heart failure or kidney failure. Another article in Critical Care Medicine shows that antibiotics typically given as a slow infusion may be safely given as a rapid IV push which may help to reach urgent time to treatment goals. Additionally, he published a recent article that is frequently cited in the medical field showing that NEWS and SIRS outperformed qSOFA as screening tools helping to detect sepsis in patients arriving to the emergency department.
Dr. Ward values providing mentorship in his work as a researcher and has been honored to collaborate with over 25 residents, fellows, and medical students on his projects.